Markopoulos has been working in the field of multimedia and installation art for several years. As with his paintings, his installations can consist of small objects as well as a room-sized environment. His enormous outdoor installations have gained the attention of an international art public. Markopoulos has participated in 120 major Exhibitions and 11 Biennials. The crowning was the official Participation in the Venice Biennale 2017 with the General Concept Essence. The conflicts of the 21st century is indisputably a reflection of the deep crisis of humanism and consequently of the concepts that have sustained the current civilizing paradigm dominated by modern thought and positivism. Markopoulos is creating physical and in 3D his multimedia artworks, installations, sculptures, and objects with concepts with the main targets of nature conservation, the protection of our most important drinking water resource, reduction of CO2 emissions. Markopoulos paintings and drawings are related to his concepts. Markopoulos Studio creates Art architecture in large scale installations, with the aim of several benefits. Markopoulos Studio believes that in order to deal with today’s challenges, Art architecture can profitably move into a field that has been largely unexplored. Markopoulos Studio has worked for a number of prestigious Real estate companies, Art Collections, Cultural institutes, private investors, and Governments.